The Baylor College of Medicine International Pediatric AIDS Initiative at Texas Children's Hospital (BIPAI), serves as the anchor for Texas Children's Global Health programs.

The mission of BIPAI and its affiliated non-governmental organizations are to provide high-quality, family-centered health care, education and clinical research worldwide.

Established in 1999 with a goal of improving the lives of HIV-infected children in Romania, BIPAI now provides HIV/AIDS, TB, malaria, malnutrition, cancer, cardiology and maternal health care and treatment, health professional education and training and clinical research through its Centers of Excellence in Romania, Botswana, Lesotho, Malawi, Swaziland, Tanzania, Uganda, Colombia and Argentina.

More than 300,000 children and their families receive care through the BIPAI network, making it the world’s largest pediatric HIV/AIDS care and treatment program. More than 100,000 healthcare professionals have been trained through its network.

BIPAI remains the world's largest academic program dedicated to global pediatric HIV/AIDS care and treatment, health professional training, monitoring, evaluation and operational research.